Services / Analytical Services for Biotechnology

MOLECULAR CYTOGENETICS SERVICE Download form Molecular Genetics Laboratory offers a complete cytogenetics service for all interested scientists. The laboratory uses the most advanced techniques to perform chromosome analysis and fluorescent in situ hybridization (FISH) analysis. Our Cytogenetics Unit has the Applied CytoVisionTM equipment & GenusTM Version 2.72 software from Applied Imaging. SERVICES • G-banding karyotyping. - Standard analysis of metaphase chromosome using G-banding technique (Karyotyping) • Fluorescence in situ hybridization (FISH) - Locus specific probes development - Gene mapping - Localization of chromosome break points - Estimation of gene copy number in interphase - Genetic evaluation of transgenic mice • Comparative Genomic Hybridization (CGH) - Chromosome loss, gain or amplification analysis - Whole genome DNA Isolation and label from microdissected cells, fresh or frozen tissue and cellular lines • Chromosome Painting including Spectral Karyotyping (SKY-FISH) - Chromosomal translocation - Chromosomal inversion • Multicolor-FISH (M-FISH) - Identification of complex structural and numerical chromosomes aberrations - Identification of chromosome anomalies that are not identifiable using traditional cytogenetic banding methods DELIVERY PROTOCOL • Blood --> Heparinized (lithium heparin) • Culture --> Medium culture (indicating it) • Tissue --> Frozen • Frozen biopsy --> Liquid nitrogen