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Drug Effect on Tumor Cell Modulation by Host-Derived Factors |
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Cancer cell behavior is critically affected by the microenvironment created by host cell-derived factors. The following tumor cell pretreatments and functional responses can be evaluated for drug effect assessment: |
Selected Tumor Cell Treatments
| DPK-DTTM-TT-01 |
|
Hypoxic atmosphere |
| DPK-DTTM-TT-02 |
|
Soluble Cell Adhesion Molecule Cocktail |
| DPK-DTTM-TT-03 |
|
Extracellular Matrix Molecule Cocktail |
| DPK-DTTM-TT-04 |
|
Growth Factor Cocktail |
| DPK-DTTM-TT-05 |
|
Oxidative stress |
| DPK-DTTM-TT-06 |
|
Neurotrophin cocktail |
| DPK-DTTM-TT-07 |
|
Organ-specific stromal cell supernantants |
|
Selected Tumor Cell Responses
| DPK-DTTM-TR-01
|
|
Adhesion molecule
expression |
| DPK-DTTM-TR-02 |
|
Proangiogenic cytokine production
|
| DPK-DTTM-TR-03 |
|
Cell proliferation |
| DPK-DTTM-TR-04 |
|
Cell apoptosis |
| DPK-DTTM-TR-05 |
|
Production of reactive oxygen species |
| DPK-DTTM-TR-06 |
|
Production of inflammatory cytokines |
| DPK-DTTM-TR-07 |
|
Cell Migration and Invasion |
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