Services / Analytical Services for Preclinical Drug Testing
Pipeline of Small Molecules under Preclinical Development Against Prometastatic and Proangiogenic Effects of Inflammation and Oxidative Stress

The following chemicals are available for licensing.

DPK-DTSM-01

VLA-4 antagonist: Unnatural small molecule that interferes with microvascular implantation and avascular growth of VLA-4-expressing cancer cells (myeloma, melanoma, ovarian carcinoma), tumor-induced osteclastogenesis and circulating endothelial progenitor cell homing in cancer tissue.

DPK-DTSM-02

Resveratrol analog: Synthetic compound 5-((E)-(4-hydroxyphenylimino)methyl)- benzene-1,3-diol that inhibits experimental metastasis formation, NFkB translocation in both cancer and host cells, and targets proangiogenic effects of tumor-activated myofibroblasts.