DPK-DTSM-01
VLA-4 antagonist: Unnatural small molecule that interferes with microvascular implantation and avascular growth of VLA-4-expressing cancer cells (myeloma, melanoma, ovarian carcinoma), tumor-induced osteclastogenesis and circulating endothelial progenitor cell homing in cancer tissue. |
DPK-DTSM-02
Resveratrol analog:
Synthetic compound 5-((E)-(4-hydroxyphenylimino)methyl)- benzene-1,3-diol
that inhibits experimental metastasis formation, NFkB translocation
in both cancer and host cells, and targets proangiogenic effects
of tumor-activated myofibroblasts. |